Structure analysis

14-3-3 Protein Theta (Human) Complexed to Peptide

X-ray diffraction
2.8Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
Accessible surface area: 22300 Å2
Buried surface area: 3700 Å2
Dissociation area: 1,000 Å2
Dissociation energy (ΔGdiss): 5 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): -25 kcal/mol
Symmetry number: 2

Macromolecules

Chains: A, B
Length: 256 amino acids
Theoretical weight: 29.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P27348 (Residues: 1-234; Coverage: 96%)
Gene name: YWHAQ
Pfam: 14-3-3 protein
InterPro:
CATH: Delta-Endotoxin; domain 1

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