PDBe 2btp

X-ray diffraction
2.8Å resolution

14-3-3 Protein Theta (Human) Complexed to Peptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein theta Chains: A, B
Molecule details ›
Chains: A, B
Length: 256 amino acids
Theoretical weight: 29.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P27348 (Residues: 1-234; Coverage: 96%)
Gene name: YWHAQ
Sequence domains: 14-3-3 protein
Structure domains: Delta-Endotoxin; domain 1
CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 6 amino acids
Theoretical weight: 796 Da
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FRE
Spacegroup: P21
Unit cell:
a: 61.307Å b: 85.964Å c: 64.666Å
α: 90° β: 112.67° γ: 90°
R-values:
R R work R free
0.21 0.206 0.259
Expression systems:
  • Escherichia coli
  • Not provided