Function and Biology

PORCINE RIBONUCLEASE INHIBITOR

Source organism: Sus scrofa
Biochemical function: ribonuclease inhibitor activity
Biological process: regulation of inflammatory response
Cellular component: angiogenin-PRI complex

Sequence families

Pfam Protein families (Pfam)
PF13516
Domain description: Leucine Rich repeat
Occurring in:
  1. Ribonuclease inhibitor
The deposited structure of PDB entry 2bnh contains 6 copies of Pfam domain PF13516 (Leucine Rich repeat) in Ribonuclease inhibitor. Showing 6 copies in chain A.

PF18779
Domain description: Capping Ribonuclease inhibitor Leucine Rich Repeat
Occurring in:
  1. Ribonuclease inhibitor
The deposited structure of PDB entry 2bnh contains 1 copy of Pfam domain PF18779 (Capping Ribonuclease inhibitor Leucine Rich Repeat) in Ribonuclease inhibitor. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001611
Domain description: Leucine-rich repeat
Occurring in:
  1. Ribonuclease inhibitor
IPR006553
Domain description: Leucine-rich repeat, cysteine-containing subtype
Occurring in:
  1. Ribonuclease inhibitor
IPR041302
Domain description: Ribonuclease inhibitor, leucine rich repeat cap
Occurring in:
  1. Ribonuclease inhibitor
IPR032675
Domain description: Leucine-rich repeat domain superfamily
Occurring in:
  1. Ribonuclease inhibitor

Structure domain

CATH CATH domain
3.80.10.10
Class: Alpha Beta
Architecture: Alpha-Beta Horseshoe
Topology: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
Homology: Ribonuclease Inhibitor
Occurring in:
  1. Ribonuclease inhibitor
The deposited structure of PDB entry 2bnh contains 1 copy of CATH domain 3.80.10.10 (Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)) in Ribonuclease inhibitor. Showing 1 copy in chain A.
SCOP SCOP annotation
52048
Class: Alpha and beta proteins (a/b)
Fold: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix)
Superfamily: RNI-like
Occurring in:
  1. Ribonuclease inhibitor
The deposited structure of PDB entry 2bnh contains 1 copy of SCOP domain 52048 (28-residue LRR) in Ribonuclease inhibitor. Showing 1 copy in chain A.