PDBe 2bkh

X-ray diffraction
2.4Å resolution

Myosin VI nucleotide-free (MDInsert2) crystal structure

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin Chain: B
Molecule details ›
Chain: B
Length: 149 amino acids
Theoretical weight: 16.83 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P62152 (Residues: 1-149; Coverage: 100%)
Gene names: CG8472, Cam
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
Unconventional myosin-VI Chain: A
Molecule details ›
Chain: A
Length: 814 amino acids
Theoretical weight: 93.03 KDa
Source organism: Sus scrofa
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q29122 (Residues: 2-816; Coverage: 65%)
Gene name: MYO6

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21
Unit cell:
a: 68.57Å b: 104.437Å c: 90.284Å
α: 90° β: 91.26° γ: 90°
R-values:
R R work R free
0.208 0.206 0.254
Expression system: Spodoptera frugiperda