PDBe 2bat

X-ray diffraction
2Å resolution

THE STRUCTURE OF THE COMPLEX BETWEEN INFLUENZA VIRUS NEURAMINIDASE AND SIALIC ACID, THE VIRAL RECEPTOR

Released:

Function and Biology Details

Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuraminidase Chain: A
Molecule details ›
Chain: A
Length: 388 amino acids
Theoretical weight: 43.14 KDa
Source organism: Influenza A virus (A/Tokyo/3/1967(H2N2))
Expression system: Not provided
UniProt:
  • Canonical: P06820 (Residues: 82-469; Coverage: 83%)
Gene name: NA
Structure domains: Neuraminidase

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I422
Unit cell:
a: 139.6Å b: 139.6Å c: 191Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 not available
Expression system: Not provided