PDBe 2b8h

X-ray diffraction
2.2Å resolution

A/NWS/whale/Maine/1/84 (H1N9) reassortant influenza virus neuraminidase

Released:

Function and Biology Details

Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuraminidase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 388 amino acids
Theoretical weight: 43.63 KDa
Source organism: Influenza A virus
Expression system: Gallus gallus
UniProt:
  • Canonical: P05803 (Residues: 83-470; Coverage: 83%)
Gene name: NA
Structure domains: Neuraminidase

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 14-BM-C
Spacegroup: P3221
Unit cell:
a: 107.516Å b: 107.516Å c: 338.487Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.141 0.139 0.189
Expression system: Gallus gallus