PDBe 2b50

X-ray diffraction
2Å resolution

Human Nuclear Receptor-Ligand Complex 2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peroxisome proliferator-activated receptor delta Chains: A, B
Molecule details ›
Chains: A, B
Length: 272 amino acids
Theoretical weight: 31.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q03181 (Residues: 169-440; Coverage: 62%)
  • Best match: Q03181-2 (Residues: 169-359)
Gene names: NR1C2, PPARB, PPARD
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21
Unit cell:
a: 39.776Å b: 92.084Å c: 95.017Å
α: 90° β: 97° γ: 90°
R-values:
R R work R free
0.199 0.197 0.249
Expression system: Escherichia coli