Function and Biology Details
Reaction catalysed:
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- SH2 domain
- Tyrosine-specific protein phosphatase, PTPase domain
- SH2 domain superfamily
- Protein-tyrosine phosphatase-like
- Protein-tyrosine phosphatase, active site
- Tyrosine-specific protein phosphatases domain
- Protein-tyrosine phosphatase, catalytic
- Protein-tyrosine phosphatase, non-receptor type-6, -11
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Tyrosine-protein phosphatase non-receptor type 6 (preferred)
PDBe Complex ID:
PDB-CPX-151411 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein phosphatase non-receptor type 6
Molecule details ›
Chain: A
Length: 532 amino acids
Theoretical weight: 60.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 532 amino acids
Theoretical weight: 60.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P29350 (Residues: 1-532; Coverage: 89%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
CHESS BEAMLINE F1
Spacegroup:
P212121
Expression system: Escherichia coli
