Assemblies
Assembly Name:
Replication protein A 70 kDa DNA-binding subunit, N-terminally processed and Cellular tumor antigen p53
Multimeric state:
hetero hexamer
Accessible surface area:
20657.3 Å2
Buried surface area:
6370.62 Å2
Dissociation area:
3,185.31
Å2
Dissociation energy (ΔGdiss):
-6.96
kcal/mol
Dissociation entropy (TΔSdiss):
50.64
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-138137
Macromolecules
Chain: A
Length: 123 amino acids
Theoretical weight: 13.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Replication factor-A protein 1, N-terminal domain
InterPro:
CATH: Nucleic acid-binding proteins
SCOP: Single strand DNA-binding domain, SSB
Length: 123 amino acids
Theoretical weight: 13.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P27694 (Residues: 1-120; Coverage: 20%)
Pfam: Replication factor-A protein 1, N-terminal domain
InterPro:
CATH: Nucleic acid-binding proteins
SCOP: Single strand DNA-binding domain, SSB
Chain: B
Length: 28 amino acids
Theoretical weight: 3.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Transactivation domain 2
InterPro: Cellular tumor antigen p53, transactivation domain 2
Length: 28 amino acids
Theoretical weight: 3.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P04637 (Residues: 33-60; Coverage: 7%)
Pfam: Transactivation domain 2
InterPro: Cellular tumor antigen p53, transactivation domain 2
