PDBe 2b1p

X-ray diffraction
1.9Å resolution

inhibitor complex of JNK3

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 10 Chain: A
Molecule details ›
Chain: A
Length: 355 amino acids
Theoretical weight: 41.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53779 (Residues: 46-400; Coverage: 77%)
Gene names: JNK3, JNK3A, MAPK10, PRKM10, SAPK1B
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 50.336Å b: 71.935Å c: 107.306Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.22 0.267
Expression system: Escherichia coli