PDBe 2awh

X-ray diffraction
2Å resolution

Human Nuclear Receptor-Ligand Complex 1


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Peroxisome proliferator-activated receptor delta Chains: A, B
Molecule details ›
Chains: A, B
Length: 268 amino acids
Theoretical weight: 30.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q03181 (Residues: 174-441; Coverage: 61%)
  • Best match: Q03181-2 (Residues: 174-359)
Gene names: NR1C2, PPARB, PPARD
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P21
Unit cell:
a: 37.22Å b: 96.717Å c: 92.304Å
α: 90° β: 89.96° γ: 90°
R R work R free
0.215 0.212 0.259
Expression system: Escherichia coli