PDBe 2aug

X-ray diffraction
2.3Å resolution

Crystal structure of the Grb14 SH2 domain


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Growth factor receptor-bound protein 14 Chains: A, B
Molecule details ›
Chains: A, B
Length: 126 amino acids
Theoretical weight: 14.63 KDa
Source organism: Homo sapiens
  • Canonical: Q14449 (Residues: 433-537; Coverage: 19%)
Gene name: GRB14
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P3121
Unit cell:
a: 49.118Å b: 49.118Å c: 184.087Å
α: 90° β: 90° γ: 120°
R R work R free
0.199 0.199 0.248