PDBe 2am9

X-ray diffraction
1.64Å resolution

Crystal structure of human androgen receptor ligand binding domain in complex with testosterone

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Androgen receptor Chain: A
Molecule details ›
Chain: A
Length: 266 amino acids
Theoretical weight: 31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P10275 (Residues: 655-920; Coverage: 29%)
Gene names: AR, DHTR, NR3C4
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 53.82Å b: 65.92Å c: 71.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.191 0.23
Expression system: Escherichia coli