PDBe 2alr

X-ray diffraction
2.48Å resolution

ALDEHYDE REDUCTASE

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
An alcohol + NADP(+) = an aldehyde + NADPH. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alcohol dehydrogenase [NADP(+)] Chain: A
Molecule details ›
Chain: A
Length: 324 amino acids
Theoretical weight: 36.49 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P14550 (Residues: 2-325; Coverage: 100%)
Gene names: AKR1A1, ALDR1, ALR
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 82.6Å b: 60Å c: 66.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.19 not available