PDBe 2aeq

X-ray diffraction
3Å resolution

An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 12-mer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Neuraminidase Chain: A
Molecule details ›
Chain: A
Length: 395 amino acids
Theoretical weight: 43.87 KDa
Source organism: Influenza A virus
  • Canonical: Q80DL0 (Residues: 75-469; Coverage: 84%)
Gene name: NA
Sequence domains: Neuraminidase
Structure domains: Neuraminidase
FAB light chain Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.78 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Ig heavy chain Mem5 Chain: H
Molecule details ›
Chain: H
Length: 217 amino acids
Theoretical weight: 23.29 KDa
Source organism: Mus musculus
  • Canonical: P84751 (Residues: 1-217; Coverage: 92%)
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P4212
Unit cell:
a: 159.753Å b: 159.753Å c: 104.113Å
α: 90° β: 90° γ: 90°
R R work R free
0.267 0.267 0.312