PDBe 2aa7

X-ray diffraction
2.2Å resolution

Mineralocorticoid Receptor with Bound Deoxycorticosterone


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Mineralocorticoid receptor Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P08235 (Residues: 712-984; Coverage: 28%)
Gene names: MCR, MLR, NR3C2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2221
Unit cell:
a: 93.009Å b: 173.407Å c: 42.123Å
α: 90° β: 90° γ: 90°
R R work R free
0.224 0.224 0.264
Expression system: Escherichia coli BL21(DE3)