PDBe 2aa2

X-ray diffraction
1.95Å resolution

Mineralocorticoid Receptor with Bound Aldosterone

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mineralocorticoid receptor Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08235 (Residues: 712-984; Coverage: 28%)
Gene names: MCR, MLR, NR3C2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2221
Unit cell:
a: 92.617Å b: 173.139Å c: 42.166Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.235
Expression system: Escherichia coli