PDBe 2a8d

X-ray diffraction
2.2Å resolution

Haemophilus influenzae beta-carbonic anhydrase complexed with bicarbonate


Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Carbonic anhydrase 2 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 229 amino acids
Theoretical weight: 26.29 KDa
Source organism: Haemophilus influenzae
Expression system: Escherichia coli
  • Canonical: P45148 (Residues: 1-229; Coverage: 100%)
Gene names: HI_1301, can
Sequence domains: Carbonic anhydrase
Structure domains: Beta-carbonic Anhydrase; Chain A

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 232.807Å b: 144.602Å c: 52.101Å
α: 90° β: 94.1° γ: 90°
R R work R free
0.206 0.206 0.24
Expression system: Escherichia coli