PDBe 2a79

X-ray diffraction
2.9Å resolution

Mammalian Shaker Kv1.2 potassium channel- beta subunit complex

Released:
Source organism: Rattus norvegicus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero 16-mer (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
poly-unknown chain Chain: C
Molecule details ›
Chain: C
Length: 52 amino acids
Theoretical weight: 4.44 KDa
Source organism: Rattus norvegicus
Expression system: Komagataella pastoris
poly-unknown chain Chain: D
Molecule details ›
Chain: D
Length: 21 amino acids
Theoretical weight: 1.81 KDa
Source organism: Rattus norvegicus
Expression system: Komagataella pastoris
Voltage-gated potassium channel subunit beta-2 Chain: A
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 37.35 KDa
Source organism: Rattus norvegicus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P62483 (Residues: 36-367; Coverage: 91%)
Gene names: Ckbeta2, Kcnab2, Kcnb3
Sequence domains: Aldo/keto reductase family
Structure domains: NADP-dependent oxidoreductase domain
Potassium voltage-gated channel subfamily A member 2 Chain: B
Molecule details ›
Chain: B
Length: 499 amino acids
Theoretical weight: 56.75 KDa
Source organism: Rattus norvegicus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P63142 (Residues: 1-499; Coverage: 100%)
Gene name: Kcna2
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: I4
Unit cell:
a: 113.605Å b: 113.605Å c: 260.473Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.222 0.252
Expression system: Komagataella pastoris