PDBe 2a2n

X-ray diffraction
1.65Å resolution

Crystal Structure of the peptidylprolyl isomerase domain of Human PPWD1

Released:

Function and Biology Details

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0). 
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidylprolyl isomerase domain and WD repeat-containing protein 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 176 amino acids
Theoretical weight: 19.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q96BP3 (Residues: 473-646; Coverage: 27%)
Gene names: KIAA0073, PPWD1
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: C2
Unit cell:
a: 139.658Å b: 39.893Å c: 115.638Å
α: 90° β: 122.33° γ: 90°
R-values:
R R work R free
0.202 0.199 0.245
Expression system: Escherichia coli BL21(DE3)