› 2a0n

X-ray diffraction
1.64Å resolution

Crystal structure of Imidazole glycerol phosphate synthase subunit hisF (EC 4.1.3.-) (tm1036) from Thermotoga maritima at 1.64 A resolution

Released:
DOI: 10.2210/pdb2a0n/pdb
PDB entry 2a0n coloured by chain, front view.
PDB entry 2a0n coloured by chain, side view.
PDB entry 2a0n coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
(1a) L-glutamine + H(2)O = L-glutamate + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194692 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Imidazole glycerol phosphate synthase subunit HisF Chain: A
Molecule details ›
Chain: A
Length: 265 amino acids
Theoretical weight: 29.22 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9X0C6 (Residues: 1-253; Coverage: 100%)
Gene names: TM_1036, hisF
Sequence domains: Histidine biosynthesis protein
Structure domains: Aldolase class I

Ligands and Environments

3 bound ligands:
Ligand IOD 7 x IOD
Ligand PO4 1 x PO4
Ligand UNL 1 x UNL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P6122
Unit cell:
a: 96.61Å b: 96.61Å c: 155.828Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.192
Expression system: Escherichia coli

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