PDBe 2zw3

X-ray diffraction
3.5Å resolution

Structure of the connexin-26 gap junction channel at 3.5 angstrom resolution

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo 12-mer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gap junction beta-2 protein Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 226 amino acids
Theoretical weight: 26.25 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P29033 (Residues: 1-226; Coverage: 100%)
Gene name: GJB2
Sequence domains: Connexin
Structure domains: Gap junction channel protein cysteine-rich domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL44XU
Spacegroup: C2
Unit cell:
a: 167.617Å b: 111.245Å c: 155.387Å
α: 90° β: 114.04° γ: 90°
R-values:
R R work R free
0.338 0.337 0.351
Expression system: Spodoptera frugiperda