PDBe 2zvo

X-ray diffraction
2.9Å resolution

NEMO CoZi domain in complex with diubiquitin in C2 space group

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin Chains: A, G
Molecule details ›
Chains: A, G
Length: 154 amino acids
Theoretical weight: 17.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CG48 (Residues: 533-684; Coverage: 22%)
Gene name: UBC
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
NF-kappa-B essential modulator Chains: B, D
Molecule details ›
Chains: B, D
Length: 92 amino acids
Theoretical weight: 10.68 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: O88522 (Residues: 250-339; Coverage: 22%)
Gene names: Ikbkg, Nemo
Structure domains: Nemo cc2-lz domain - 1d5 darpin complex

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-17A
Spacegroup: C2
Unit cell:
a: 130.861Å b: 98.372Å c: 50.616Å
α: 90° β: 101.96° γ: 90°
R-values:
R R work R free
0.24 0.237 0.277
Expression system: Escherichia coli