PDBe 2z8w

X-ray diffraction
2.45Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Apical membrane antigen 1, AMA1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 335 amino acids
Theoretical weight: 38.36 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7KQK5 (Residues: 104-438; Coverage: 56%)
Gene names: AMA1, PF11_0344, PF3D7_1133400
Structure domains: Hepatocyte Growth Factor
New antigen receptor variable domain Chains: C, D
Molecule details ›
Chains: C, D
Length: 116 amino acids
Theoretical weight: 12.86 KDa
Source organism: Orectolobus maculatus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6X1E6 (Residues: 1-113; Coverage: 100%)
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-18B
Spacegroup: P31
Unit cell:
a: 76.48Å b: 76.48Å c: 140.978Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.198 0.189 0.282
Expression systems:
  • Escherichia coli BL21(DE3)
  • Escherichia coli