PDBe 2y5y

X-ray diffraction
3.38Å resolution

Crystal structure of LacY in complex with an affinity inactivator


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Lactose permease Chains: A, B
Molecule details ›
Chains: A, B
Length: 423 amino acids
Theoretical weight: 47.27 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli K-12
  • Canonical: P02920 (Residues: 1-417; Coverage: 100%)
Gene names: JW0334, b0343, lacY
Sequence domains: LacY proton/sugar symporter
Structure domains: MFS general substrate transporter like domains

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P212121
Unit cell:
a: 102.56Å b: 127.84Å c: 189.87Å
α: 90° β: 90° γ: 90°
R R work R free
0.287 0.286 0.303
Expression system: Escherichia coli K-12