PDBe 2x2e

X-ray diffraction
2Å resolution

Dynamin GTPase dimer, long axis form


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Dynamin-1 Chains: A, D
Molecule details ›
Chains: A, D
Length: 353 amino acids
Theoretical weight: 39.76 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q05193 (Residues: 6-320; Coverage: 37%)
Gene names: DNM, DNM1
Sequence domains: Dynamin family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 43.61Å b: 81.02Å c: 181.54Å
α: 90° β: 90° γ: 90°
R R work R free
0.185 0.185 0.23
Expression system: Escherichia coli BL21(DE3)