PDBe 2wxw

X-ray diffraction
3.3Å resolution

Crystal structure of human angiotensinogen


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Angiotensinogen Chain: A
Molecule details ›
Chain: A
Length: 453 amino acids
Theoretical weight: 49.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P01019 (Residues: 34-485; Coverage: 100%)
Gene names: AGT, SERPINA8
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: P41212
Unit cell:
a: 133.285Å b: 133.285Å c: 123.602Å
α: 90° β: 90° γ: 90°
R R work R free
0.31 0.309 0.318
Expression system: Escherichia coli BL21(DE3)