PDBe 2wvr

X-ray diffraction
3.3Å resolution

Human Cdt1:Geminin complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Geminin Chains: A, B
Molecule details ›
Chains: A, B
Length: 209 amino acids
Theoretical weight: 23.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75496 (Residues: 1-209; Coverage: 100%)
Gene name: GMNN
Sequence domains: Geminin
Structure domains: Geminin coiled-coil domain
DNA replication factor Cdt1 Chain: C
Molecule details ›
Chain: C
Length: 546 amino acids
Theoretical weight: 60.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H211 (Residues: 1-546; Coverage: 100%)
Gene name: CDT1
Sequence domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P43212
Unit cell:
a: 92.804Å b: 92.804Å c: 164.842Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.243 0.24 0.301
Expression system: Escherichia coli