PDBe 2wp3

X-ray diffraction
1.48Å resolution

Crystal structure of the Titin M10-Obscurin like 1 Ig complex

Released:
Source organism: Homo sapiens

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Obscurin-like protein 1 Chain: O
Molecule details ›
Chain: O
Length: 109 amino acids
Theoretical weight: 11.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75147 (Residues: 1-106; Coverage: 6%)
Gene names: KIAA0657, OBSL1
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins
Titin Chain: T
Molecule details ›
Chain: T
Length: 102 amino acids
Theoretical weight: 10.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WZ42 (Residues: 34252-34350; Coverage: 0%)
Gene name: TTN
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P31
Unit cell:
a: 61.674Å b: 61.674Å c: 42.347Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.178 0.176 0.217
Expression system: Escherichia coli