PDBe 2wk5

X-ray diffraction
2.99Å resolution

Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thymidine phosphorylase Chains: A, B, C, D

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P21
Unit cell:
a: 103.532Å b: 77.188Å c: 100.878Å
α: 90° β: 98.04° γ: 90°
R-values:
R R work R free
0.207 0.207 0.284
Expression system: Escherichia coli BL21(DE3)