PDBe 2wfq

X-ray diffraction
1.85Å resolution

Crystal structure of the N-terminal signalling domain of human Dhh without calcium


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Desert hedgehog protein N-product Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 18.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O43323 (Residues: 39-195; Coverage: 42%)
Gene name: DHH
Structure domains: Muramoyl-pentapeptide Carboxypeptidase; domain 2

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 40.563Å b: 42.048Å c: 84.301Å
α: 90° β: 90° γ: 90°
R R work R free
0.189 0.187 0.229
Expression system: Escherichia coli