PDBe 2vzd

X-ray diffraction
2.1Å resolution

Crystal structure of the C-terminal calponin homology domain of alpha parvin in complex with paxillin LD1 motif

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Paxillin Chains: C, D
Molecule details ›
Chains: C, D
Length: 20 amino acids
Theoretical weight: 2.18 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49023 (Residues: 1-20; Coverage: 3%)
Gene name: PXN
Alpha-parvin Chains: A, B
Molecule details ›
Chains: A, B
Length: 131 amino acids
Theoretical weight: 15.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9NVD7 (Residues: 242-372; Coverage: 35%)
Gene names: MXRA2, PARVA
Sequence domains: Calponin homology (CH) domain
Structure domains: Actin-binding Protein, T-fimbrin; domain 1

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 133.123Å b: 37.503Å c: 70.244Å
α: 90° β: 90.33° γ: 90°
R-values:
R R work R free
0.219 0.217 0.255
Expression systems:
  • Not provided
  • Escherichia coli BL21