PDBe 2voo

X-ray diffraction
1.8Å resolution

Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer UUUUUUUU

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Lupus La protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 193 amino acids
Theoretical weight: 22.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05455 (Residues: 4-194; Coverage: 47%)
Gene name: SSB
Sequence domains:
Structure domains:
5'-R(*UP*UP*UP*UP*UP*UP*UP)-3' Chains: C, D
Molecule details ›
Chains: C, D
Length: 7 nucleotides
Theoretical weight: 2.1 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P21212
Unit cell:
a: 98.309Å b: 114.586Å c: 37.41Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.25 0.25 0.279
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided