› 2vl7

X-ray diffraction
2.25Å resolution

Structure of S. tokodaii Xpd4

Released:
DOI: 10.2210/pdb2vl7/pdb
PDB entry 2vl7 coloured by chain, front view.
PDB entry 2vl7 coloured by chain, side view.
PDB entry 2vl7 coloured by chain, top view.
Source organism: Sulfurisphaera tokodaii
Primary publication:
Structure of the DNA repair helicase XPD.
Liu H, Rudolf J, Johnson KA, McMahon SA, Oke M, Carter L, McRobbie AM, Brown SE, Naismith JH, White MF
Cell 133 801-12 (2008)
PMID: 18510925

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188818 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Helicase ATP-binding domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 540 amino acids
Theoretical weight: 62.33 KDa
Source organism: Sulfurisphaera tokodaii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q971R4 (Residues: 1-540; Coverage: 100%)
Gene names: ST1307, STK_13070, xpd
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21212
Unit cell:
a: 95.713Å b: 100.294Å c: 62.488Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.232 0.276
Expression system: Escherichia coli

Quick links

Citations

54 review citations

Understanding nucleotide excision repair and its roles in cancer and ageing.
Marteijn et al. (2014)
53 more

7 mentions without citation

Two steps forward, one step back: determining XPD helicase mechanism by single-molecule fluorescence and high-resolution optical tweezers.
Spies M. (2014)
6 more