PDBe 2vgg

X-ray diffraction
2.74Å resolution

HUMAN ERYTHROCYTE PYRUVATE KINASE: R479H MUTANT

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pyruvate kinase PKLR Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 528 amino acids
Theoretical weight: 56.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P30613 (Residues: 47-574; Coverage: 92%)
Gene names: PK1, PKL, PKLR
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7A
Spacegroup: P21
Unit cell:
a: 74.036Å b: 171.795Å c: 85.086Å
α: 90° β: 91.17° γ: 90°
R-values:
R R work R free
0.254 0.253 0.294
Expression system: Escherichia coli BL21