PDBe 2v5n

X-ray diffraction
3.2Å resolution

STRUCTURE OF HUMAN IGF2R DOMAINS 11-12

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation-independent mannose-6-phosphate receptor Chain: A
Molecule details ›
Chain: A
Length: 299 amino acids
Theoretical weight: 32.98 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: NEW P11717 (Residues: 1508-1800; Coverage: 12%)
Gene names: IGF2R, MPRI
Sequence domains: Cation-independent mannose-6-phosphate receptor repeat
Structure domains: Mannose-6-phosphate receptor binding domain

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P6122
Unit cell:
a: 64.793Å b: 64.793Å c: 269.569Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.259 0.253 0.317
Expression system: Cricetulus griseus