PDBe 2rvq

Solution NMR

Solution structure of the isolated histone H2A-H2B heterodimer

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Histone H2A type 1-B/E Chain: C
Molecule details ›
Chain: C
Length: 133 amino acids
Theoretical weight: 14.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P04908 (Residues: 1-130; Coverage: 100%)
Gene names: H2AFA, H2AFM, HIST1H2AB, HIST1H2AE
Sequence domains:
Structure domains: Histone, subunit A
Histone H2B type 1-J Chain: D
Molecule details ›
Chain: D
Length: 129 amino acids
Theoretical weight: 14.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P06899 (Residues: 1-126; Coverage: 100%)
Gene names: H2BFR, HIST1H2BJ
Sequence domains: Core histone H2A/H2B/H3/H4
Structure domains: Histone, subunit A

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 38%
Refinement method: CS-Rosetta-AbinitioRelax, CS-Rosetta-FloppyTail
Chemical shifts: BMR11609  
Expression system: Escherichia coli