PDBe 2rqu

Solution NMR

Solution structure of the complex between the DDEF1 SH3 domain and the APC SAMP1 motif

Released:

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 61 amino acids
Theoretical weight: 7.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9ULH1 (Residues: 1069-1129; Coverage: 5%)
Gene names: ASAP1, DDEF1, KIAA1249
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Adenomatous polyposis coli protein Chain: B
Molecule details ›
Chain: B
Length: 19 amino acids
Theoretical weight: 2.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P25054 (Residues: 1578-1596; Coverage: 1%)
Gene names: APC, DP2.5

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: torsion angle dynamics, simulated annealing
Chemical shifts: BMR11082  
Expression system: Escherichia coli