PDBe 2rhp

X-ray diffraction
2.9Å resolution

The Thrombospondin-1 Polymorphism Asn700Ser Associated with Cornoary Artery Disease Causes Local and Long-Ranging Changes in Protein Structure

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thrombospondin-2 Chain: A
Molecule details ›
Chain: A
Length: 622 amino acids
Theoretical weight: 69.3 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: NEW P35442 (Residues: 551-1172; Coverage: 54%)
Gene names: THBS2, TSP2
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: I222
Unit cell:
a: 93.892Å b: 122.65Å c: 155.381Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.229 0.227 0.277
Expression system: Spodoptera frugiperda