PDBe 2rdw

X-ray diffraction
1.95Å resolution

Crystal Structure of Human Glycolate Oxidase in Complex with Sulfate

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hydroxyacid oxidase 1 Chain: A
Molecule details ›
Chain: A
Length: 387 amino acids
Theoretical weight: 42.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UJM8 (Residues: 1-370; Coverage: 100%)
Gene names: GOX1, HAO1, HAOX1
Sequence domains: FMN-dependent dehydrogenase
Structure domains: Aldolase class I

Ligands and Environments


Cofactor: Ligand FMN 1 x FMN
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X4A
Spacegroup: I422
Unit cell:
a: 143.649Å b: 143.649Å c: 110.461Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.235
Expression system: Escherichia coli