PDBe 2pm5

X-ray diffraction
2.4Å resolution

Human alpha-defensin 1 derivative (HNP1)

Source organism: Homo sapiens
Entry authors: Lubkowski J, Pazgier M, Lu W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
homo dimer
Entry contents:
1 distinct polypeptide molecule
Neutrophil defensin 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 30 amino acids
Theoretical weight: 3.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P59666 (Residues: 66-94; Coverage: 39%)
Gene names: DEF3, DEFA3
Sequence domains: Mammalian defensin

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P4222
Unit cell:
a: 57.409Å b: 57.409Å c: 96.967Å
α: 90° β: 90° γ: 90°
R R work R free
0.201 0.2 0.218
Expression system: Escherichia coli