PDBe 2p64

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
F-box/WD repeat-containing protein 1A Chains: A, B
Molecule details ›
Chains: A, B
Length: 52 amino acids
Theoretical weight: 6.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9Y297 (Residues: 128-177; Coverage: 8%)
Gene names: BTRC, BTRCP, FBW1A, FBXW1A
Sequence domains: D domain of beta-TrCP

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 8-BM
Spacegroup: P43212
Unit cell:
a: 71.316Å b: 71.316Å c: 116.301Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.239 0.267
Expression system: Escherichia coli BL21