PDBe 2p2l

X-ray diffraction
1.9Å resolution

Rac1-GDP-Zinc Complex

Source organism: Homo sapiens
Primary publication:
A Rac1-GDP trimer complex binds zinc with tetrahedral and octahedral coordination, displacing magnesium.
Acta Crystallogr. D Biol. Crystallogr. 63 628-35 (2007)
PMID: 17452788

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo trimer (preferred)
homo hexamer
Entry contents:
1 distinct polypeptide molecule
Ras-related C3 botulinum toxin substrate 1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 188 amino acids
Theoretical weight: 20.79 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: NEW P63000 (Residues: 1-184; Coverage: 96%)
Gene names: MIG5, RAC1, TC25
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X3A
Spacegroup: P3221
Unit cell:
a: 89.727Å b: 89.727Å c: 190.618Å
α: 90° β: 90° γ: 120°
R R work R free
0.177 0.176 0.208
Expression system: Escherichia coli BL21(DE3)