PDBe 2oj9

X-ray diffraction
2Å resolution

Structure of IGF-1R kinase domain complexed with a benzimidazole inhibitor


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Insulin-like growth factor 1 receptor beta chain Chain: A
Molecule details ›
Chain: A
Length: 307 amino acids
Theoretical weight: 35.04 KDa
Source organism: Homo sapiens
Expression system: unidentified baculovirus
  • Canonical: P08069 (Residues: 982-1286; Coverage: 23%)
Gene name: IGF1R
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 57.271Å b: 44.289Å c: 65.744Å
α: 90° β: 99.05° γ: 90°
R R work R free
0.217 0.214 0.276
Expression system: unidentified baculovirus