PDBe 2o72

X-ray diffraction
2Å resolution

Crystal Structure Analysis of human E-cadherin (1-213)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cadherin-1 Chain: A
Molecule details ›
Chain: A
Length: 213 amino acids
Theoretical weight: 23.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12830 (Residues: 155-367; Coverage: 25%)
Gene names: CDH1, CDHE, UVO
Sequence domains: Cadherin domain
Structure domains: Cadherins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 137.341Å b: 41.077Å c: 59.542Å
α: 90° β: 111.15° γ: 90°
R-values:
R R work R free
0.226 0.191 0.234
Expression system: Escherichia coli