PDBe 2nsn

X-ray diffraction
2Å resolution

Crystal structure of Caspace Activation and Recruitment Domain (CARD) of NOD1

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of the Nod1 caspase activation and recruitment domain.
Biochem. Biophys. Res. Commun. 353 1-5 (2007)
PMID: 17173864

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleotide-binding oligomerization domain-containing protein 1 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y239 (Residues: 16-108; Coverage: 10%)
Gene names: CARD4, NOD1
Sequence domains: Caspase recruitment domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P41212
Unit cell:
a: 40.141Å b: 40.141Å c: 150.748Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.222 0.221 0.262
Expression system: Escherichia coli BL21(DE3)