PDBe 2n1a

Solution NMR

Docked structure between SUMO1 and ZZ-domain from CBP

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Small ubiquitin-related modifier 1 Chain: A
Molecule details ›
Chain: A
Length: 103 amino acids
Theoretical weight: 11.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: NEW P63165 (Residues: 1-101; Coverage: 100%)
Gene names: OK/SW-cl.43, SMT3C, SMT3H3, SUMO1, UBL1
Sequence domains: Ubiquitin-2 like Rad60 SUMO-like
CREB-binding protein Chain: B
Molecule details ›
Chain: B
Length: 53 amino acids
Theoretical weight: 6.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: NEW Q92793 (Residues: 1699-1751; Coverage: 2%)
Gene names: CBP, CREBBP
Sequence domains: Zinc finger, ZZ type
Structure domains: Wheat Germ Agglutinin (Isolectin 2); domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 10%
Refinement method: simulated annealing
Chemical shifts: BMR25553  
Expression system: Escherichia coli BL21(DE3)