PDBe 2mwy

Solution NMR

Mdmx-p53

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein Mdm4 Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 10.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O15151 (Residues: 23-111; Coverage: 18%)
Gene names: MDM4, MDMX
Sequence domains: SWIB/MDM2 domain
Structure domains: SWIB/MDM2 domain
Cellular tumor antigen p53 Chain: B
Molecule details ›
Chain: B
Length: 15 amino acids
Theoretical weight: 1.81 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04637 (Residues: 15-29; Coverage: 4%)
Gene names: P53, TP53

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 34%
Chemical shifts: BMR25377  
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided