PDBe 2ms4

Solution NMR

Cyclophilin a complexed with a fragment of crk-ii

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Peptidyl-prolyl cis-trans isomerase A Chain: A
Molecule details ›
Chain: A
Length: 165 amino acids
Theoretical weight: 18.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: NEW P62937 (Residues: 1-165; Coverage: 100%)
Gene names: CYPA, PPIA
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like
Adapter molecule crk Chain: B
Molecule details ›
Chain: B
Length: 9 amino acids
Theoretical weight: 955 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: NEW P46108 (Residues: 216-224; Coverage: 3%)
Gene name: CRK

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Chemical shifts: BMR25104  
Expression systems:
  • Escherichia coli
  • Not provided