PDBe 2mgt

Solution NMR

Zinc induced dimer of the metal binding domain 1-16 of human amyloid beta-peptide with Alzheimer's disease pathogenic English mutation H6R


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Amyloid-beta protein 40 Chains: A, B
Molecule details ›
Chains: A, B
Length: 18 amino acids
Theoretical weight: 2 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: P05067 (Residues: 672-687; Coverage: 2%)
Gene names: A4, AD1, APP

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 40%
Refinement method: simulated annealing
Chemical shifts: BMR19602  
Expression system: Not provided